Pharma Marketletter - Novartis’ Diovan as effective as Norvasc in hypertensive patients with high CVD risk.

Results have been published in The Lancet from the eagerly-awaited VALUE (Valsartan Antihypertensive Long-term Use Evaluation) trial, which compared Novartis’ angiotensin II receptor blocker Diovan (valsartan) with Pfizer’s calcium antagonist Norvasc (amlodipine) in hypertensive patients at high cardiovascular risk.

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The prospective, double-blind, randomized, active-controlled study involved 15,245 high blood pressure patients at risk for cardiovascular complications because of co-existing diseases or risk factors such as diabetes, history of stroke and coronary heart disease. The trial was primarily designed to evaluate, …
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